The ATP6V1E1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ATP6V0E, and ATP6V0E1. This antibody recognizes Human, Mouse, and Rat antigen. The ATP6V1E1 Polyclonal Antibody has been validated for the following applications: Immunohistochemistry, Immunoprecipitation, and Western Blot.
Description
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain E subunit isoforms. Pseudogenes for this gene have been found in the genome